Can you overdose on cannabis? This question is controversial, even among people who frequently use cannabis. Some people believe cannabis is as dangerous as opioids or stimulants, while others believe it’s completely harmless and has no side effects.

You can’t overdose on cannabis in the way that you can overdose on, say, opioids. To date, there have not been any reported deaths resulting solely from cannabis use, according to the Centers for Disease Control and Prevention (CDC).

But that doesn’t mean you can’t overdo it or have a bad reaction to cannabis.

Marijuana (cannabis) has a reputation for being a totally benign drug. To read the claims from the proponents of weed, it would seem that cannabis only has beneficial effects. Ask any stoner from the 60s about their bad experiences and it becomes clear that marijuana isn’t always rainbows and unicorns.

There is plenty of evidence that, as drugs go, marijuana is significantly less dangerous than many other oft-abused substances, including alcohol. But less dangerous is a far cry from saying it’s completely safe.

Marijuana Overdose

thc overdose

Marijuana doesn’t come with a clear definition of overdose. In fact, doctors aren’t entirely sure how much tetrahydrocannabinol (THC) it takes to overdose. THC is the active ingredient in marijuana most likely to induce the high users are seeking.

Risk of Death

Some wonder if marijuana overdose can cause death. There have been a few isolated case reports where marijuana has been implicated in people’s death. However, a clear causal relationship has not been established.

What medical professionals aren’t clear about, is whether those cases had other contributing factors (like pre-existing cardiac conditions).How to Recognize the Signs of a Drug Overdose

Other Adverse Effects

Marijuana is a strange drug in that it contains a lot of active ingredients. Although scientists cite different numbers, in addition to THC, there are thought to be over 100 other cannabinoids in cannabis. Not all of these act the same way.

Get too much THC and you may have a psychoactive reaction that is not unlike that of a stimulant. Cannabidiol (CBD) is associated more with sedative effects. 

The effects of marijuana use are all over the map. There have been cases of heart arrhythmias and sudden cardiac arrest while smoking weed. There are reports of both seizures and the reduction of seizures, which seems to be based on which type of cannabinoid and at what amounts are used.

Here are some examples of THC toxicity that have been published:

  • Heart arrhythmias: Some doctors believe that heart disturbances are under-reported in marijuana use.1 Since smoking weed and taking other drugs often go together, it’s really hard to isolate the cause when the heart starts doing crazy things. Even drinking alcohol intensifies the effects, which means you can’t say for sure whether it was the pot or the booze that caused a problem.
  • Psychosis or paranoia: Users report severe psychotic episodes with hallucinations and negative associations.2 In some cases, the psychosis can last significantly longer than the amount of time it should take to metabolize the THC.
  • Uncontrollable vomiting: Although THC often has anti-nausea properties, it can rarely be associated with a syndrome of persistent vomiting. More often associated with chronic cannabis use, uncontrollable vomiting is sometimes relieved with a hot shower.

What does a bad reaction look like?

Cannabis can have quite a few less-than-desirable side effects, including:

  • confusion
  • thirstiness or a dry mouth (aka “cotton mouth”)
  • concentration problems
  • slower reaction times
  • dry eyes
  • fatigue or lethargy
  • headaches
  • dizziness
  • increased heart rate
  • anxiety and other changes in mood

In rarer cases, it can also cause:

  • hallucinations
  • paranoia and panic attacks
  • nausea and vomiting

These side effects can last anywhere from 20 minutes to a full day. In general, cannabis that’s higher in THC is associated with more severe, long-lasting effects. And yes, it’s possible to wake up with a “weed hangover” the following day.

How to handle it

If you or a friend has overindulged, there are a few things you can do to reduce the unpleasant side effects.

Relax

If you’re feeling anxious, it’s good to self-soothe by telling yourself that you’ll be OK. Remind yourself that nobody has ever died from a cannabis overdose.

It might not feel like it right now, but these symptoms will pass.

Eat something

If you’re feeling nauseated or shaky, try to have a snack. This might be the last thing you want to do, especially if you also have dry mouth, but it makes a big difference for some people.

Drink water

Speaking of dry mouth, make sure you drink plenty of liquids. This is especially important if you’re vomiting, which can dehydrate you.

If you’re panicking, try slowly sipping water to help ground yourself.

Sleep it off

Sometimes, the best thing to do is wait for the effects to subside. Sleeping or resting is a good way to pass time while you wait for the cannabis to work its way out of your system.

Avoid overstimulation

If too much is happening around you, it can make you anxious and even paranoid.

Switch off the music or TV, leave the crowd, and try to relax in a calm environment, like an empty bedroom or bathroom.

Chew or sniff black peppercorns

Anecdotally, many people swear that black peppercorns can soothe the side effects of overindulging in cannabis, especially anxiety and paranoia.

According to research, black peppercorns contain caryophyllene, which might weaken the uncomfortable effects of THC. But this remedy hasn’t been rigorously studied, and there is no evidence in humans to support it.

Call a friend

thc overdose

It may be helpful to call a friend who has experience with cannabis. They may be able to talk you through the unpleasant experience and calm you down.

Is it an emergency?

Having a bad reaction to cannabis usually isn’t a medical emergency.

However, if someone is experiencing hallucinations or signs of psychosis, it’s important to get emergency help.

Cannabis tips

Looking to avoid a bad reaction in the future?

Keep the following in mind:

  • Start with low doses. If it’s your first time using cannabis, it’s a good idea start low and slow. Consume a small amount and give it plenty of time to kick in before using more.
  • Be careful with edibles. Edibles take anywhere from 20 minutes up to 2 hours to kick in because they need to be digested first. If you’re trying edibles for the first time, or if you’re not sure of the strength, have a very small amount and wait at least 2 hours before having more.
  • Try a low-THC cannabis product. Most dispensaries and cannabis shops list the amount of THC in their products. If you’re new to cannabis, or if you’re sensitive to the side effects, try a low-THC product or one with a high CBD:THC ratio.
  • Avoid overwhelming situations. If cannabis sometimes makes you anxious or confused, it might be best to use it in a safe, calm environment.

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